If you're a collector or interested in historical medical literature, this book is a great addition. To handle it, always wash your hands before opening to avoid dirt and oil transfer. When reading, use a bookmark instead of folding pages to prevent damage. Store it in a cool, dry place away from direct sunlight to slow down darkening and foxing. If you notice any loose pages, you can take it to a professional bookbinder for repair. Enjoy exploring the historical medical knowledge within this antique book!